Chemerin: A Multifaceted Biomarker in Metabolism and Disease
Immunology / Cytokines
Key Points about Chemerin:
Protein Characteristics
- 157 amino acid protein
- Produced by RARRES2 gene
- Activated by serine proteases
- Primarily binds to ChemR23 receptor
Biological Functions
- Adipogenesis and metabolic regulation
- Immune system signaling
- Inflammation control
- Glucose and insulin sensitivity management
Clinical Implications
- Linked to obesity and metabolic syndrome
- Associated with type 2 diabetes
- Indicates cardiovascular disease risk
- Connected to inflammatory conditions
- Potential role in cancer biology
Measurement
- Detected via ELISA methods
- Blood serum/plasma analysis
Therapeutic Potential
- Target for drug development
- Possible intervention in:
- Obesity
- Insulin resistance
- Cardiovascular diseases
- Inflammatory disorders
Future Research Directions
- Long-term disease progression studies
- Clinical trials on chemerin treatments
- Exploring biomarker applications
- Investigating varied disease interactions
Chemerin represents a complex biomarker with significant potential in understanding metabolic and inflammatory processes.
Suitable ELISA Kits
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