ICTP: Cross-Linked C-Terminal Telopeptide of Collagen Alpha-1(I) Chain - A Biomarker of Bone Resorption
Endocrinology Diagnostics
Key Points about ICTP:
Protein Characteristics
- Derived from type I collagen
- Cross-linked peptide fragment
- Breakdown product of collagen
Biological Significance
- Bone resorption indicator
- Measures collagen degradation
- Tracks bone turnover rate
Clinical Applications
- Osteoporosis monitoring
- Bone metastasis detection
- Cancer progression assessment
- Metabolic bone disease evaluation
Diagnostic Methods
- Serum/plasma sampling
- Immunoassay techniques
- Standardized measurement protocols
Disease Monitoring
- Cancer metastasis tracking
- Treatment response evaluation
- Rheumatoid arthritis assessment
- Multiple myeloma monitoring
Future Research Directions
- Improved detection methods
- Novel measurement techniques
- Personalized medicine applications
- Enhanced diagnostic tools
ICTP serves as a critical biomarker for understanding bone metabolism, disease progression, and treatment effectiveness across multiple medical conditions.
Suitable ELISA Kits
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